Landscape and challenges in economic evaluations of artificial intelligence in healthcare: a systematic review of methodology

Kastrup, Nanna; Holst-Kristensen, Annette W.; Valentin, Jan B.

doi:10.1186/s44247-024-00088-7

Table 2 Health economic characteristics of the included HEEs (n =29)

From: Landscape and challenges in economic evaluations of artificial intelligence in healthcare: a systematic review of methodology

Author	Settings	Perspective	HEE type	DAM type or ACL	Primary outcome	ICER	Cost- effective alternative
Delgadillo et al.	Psychological therapy services	Health service	CEA	ACL	PHQ-9 measure	CT	Intervention
Fuller et al.	Primary care	Payer	CUA	Markov	QALY	$258,721.81/QALY	Intervention
Rossi et al.	CT	Payer	CUA	Markov	QALY	−$27,580/QALY	CT
Rossi et al.	CT	Payer	CEA	Markov	Tooth retention time	−€15.01/year	CT
Rossi et al.	CT	Payer	CUA	Markov	QALY	R-$91,760/QALY	CT
Hill et al.	Primary care	National health service	CUA	Decision tree and Markov	QALY	Systematic: £4,847/QALY Opportunistic: £5,544/QALY	Intervention
Huang et al.	Health service stations	Health system and societal	CUA	Decision tree and Markov	QALY	Health system: $1,107.63/QALY Societal: $1,0347.12/QALY	Intervention
Mervin et al.	Long-term care facilities	Healthcare	CEA	ACL	CMAI-SF	PARO: $13.01/CMAI-SF Plush toy: $12.85/CMAI-SF	CT
Morrison et al.	CT	Healthcare	CEA	Decision tree	QALY	CT	CT
Nsengiyumva et al.	Health centre	Healthcare	CEA	Decision tree	DALY	CT	CT
Padula et al.	Hospital	Societal and healthcare	CUA	Markov	QALY	Healthcare: $2,142/QALY Societal: $2,000/QALY	Intervention
Schwendicke et al.	Private dental practice	Healthcare	CEA	ACL	Tooth retention time	− €8.9/year	Control
Schwendicke et al.	CT	Public-private-payer healthcare	CEA	Markov	Tooth retention time	− €13.9 /year	Intervention
Tseng et al.	CT	Healthcare	CUA	Decision tree and Markov	QALY	$43,351/QALY	Intervention
Wolf et al.	CT	Family	CEA	Decision tree	True positive proportion	T1DM: $31/TPP T2DM: $95/TPP	Intervention
Turino et al.	Hospital sleep unit	CT	CEA	ACL	Hours/day of CPAP use	CT	Intervention
Mallow et al.	Orthopaedic pain management	Payer and self-insured payer	CUA	Markov	QALY	CT	Intervention
Barkun et al.	Health care	Payer’s perspective	CUA	Markov	QALY and LY	CT	Intervention
Chawla et al.	Primary care	Health care payer	CUA	Markov	QALY	CT	Intervention
Hassan et al.	Primary screening	National health service	CUA	Markov	QALY	CT	Intervention
Hill et al.	Primary care	National health service	CUA	Decision tree and Markov	QALY	£3,994/QALY	Intervention
Lin et al.	Community health service center	Societal	CEA and CUA	Markov	Years without blindness per 100,000 people with DM, and QALY	ICER: $2553.39/year ICUR: $15,216.96/ QALY	Control
Mital et al.	CT	Health care system	CUA	Decision tree and microsimulation	QALY	$23,755/QALY	Intervention
Pickhardt et al.	CT	CT	CUA	Markov	QALY	CT	Intervention
Shen et al.	Primary screening	Health care provider	CUA	Markov	QALY	$622–24,482/QALY	Intervention
Skarping et al.	CT	Health care	CUA	Decision tree	QALY	CT	Intervention
Srisubat et al.	CT	Health care provider and societal	CUA	Decision tree and Markov	QALY	Provider: $512,955/QALY Societal: CT	CT
Yonazu et al.	CT	Medical payer	CUA	Decision tree and Markov	QALY	$11,0937QALY	Intervention
Ziegelmayer et al.	CT	Health care	CUA	Markov	QALY	CT	Intervention

Key: HEE Health economic evaluation, PHQ-9 Patient health questionnaire, CT Cannot tell, CEA Cost-effectiveness analysis, CUA Cost-utility analysis, QALY Quality-adjusted life years, NHS National health service, DALY Disability-adjusted life year, TTP True positive proportion, ACL Alongside clinical trial, T1DM Type-1 diabetes mellitus, T2DM Type-2 diabetes mellitus, PHQ Patient health questionnaire, CPAP Continuous positive airway pressure, CMAI-SF Cohen–Mansfield Agitation Inventory-Short Form, DAM Decision-analytic model, ICER Incremental cost-effectiveness ratio, TPP True positive proportion, DM Diabetes mellitus, ANN Artificial Neural Network

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ISSN: 2731-684X

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