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Table 1 Blockchain technologies relevant to Global Patient Co-Owned Cloud (GPOC) in healthcare: overview and potential applications

From: Technical sandbox for a Global Patient co-Owned Cloud (GPOC)

Name

Algorithm

Programmable

Relevance

Bitcoin

Proof of work

Yes (scripts)

The most well-known blockchain, which token has the highest crypto value. Energy inefficient at present for a GPOC

Litecoin

Proof of work

Yes (scripts)

An open-source peer to peer cryptocurrency. May be inefficient for GPOC

Primecoin

Proof of work

Yes

Long Cunningham chains of prime numbers is the centre of the blockchain. May be inefficient for a GPOC

Ethereum

Proof of work/ Migrated to Proof of Stake

Yes

After Bitcoin, the most valuable token. Recently attracted attention to its grand merge where it tried to switch to proof of stake, for energy consumption reasons. Programmable widely supported smart contracts

Peercoin

Proof of stake/Proof of Work

Yes (scripts)

An early pioneering blockchain that is presented as being sustainable. May be slower than other networks with a 10 min block-time. May have applications for the GPOC

Bitcoin Cash

Proof of work

Yes

Derived from Bitcoin. At present may be too energy inefficient for GPOC

Cardano

Proof of stake

Yes

First to be founded on peer-reviewed research and evidence-based methods that is currently integrating smart contract technology. May have applications for GPOC

Tezos

Proof of stake

Yes

User-governed & user-centric movement

Bitcoin SV

Proof of work

Yes (scripts)

A second-generation spin-off from Bitcoin

Hedera Hashgraph

Asynchronous Byzantine Fault-Tolerant (aBFT) consensus

Yes

Does not use a classic blockchain, but a directed acyclic graph. It may apply to a GPOC system as it is privacy-enabled and GDPR compliant

Zcash

Zero Knowledge proof

Yes

Zero-knowledge proofs for privacy protection but a digital currency. It is like the Mina protocol, using ZK-Snarks with a 75-s block time

Monero

Proof of work

No

Anonymous, untraceable, undecipherable. It has a two-minute block time. However, may be energy inefficient for a GPOC

Bitcoin Gold

Proof of work

Yes (scripts)

Mined on common GPUs instead of specialty ASICs. Energy inefficient for GPOC at present

IOTA

Proof of work, TaPoW

No

Designed for Internet of Things (IoT). May be applicable for the GPOC due to its DAG-based form

Solana

Proof of Stake

Yes, with Rust

Scalable operates on Berkeley Packet Filter with a fast 400 ms block time. May have applications for a GPOC

  1. Blockchains that may be relevant to GPOC. Such healthcare networks can share and procure sensitive patient data. It can be exchanged between laboratories, clinics, hospitals, and caregivers. Applications of these decentralised blockchains can be used to accurately identify mistakes. Hence, we provide an overview of common blockchains relevant to healthcare and their potential use for GPOC. Blockchains may be the cusp of a new healthcare era [38,39,40,41,42,43,44,45,46,47,48,49,50].